Labchip gxii touch biotherapeutics how a chip works. The file types created by the ice cfr software have the extensions icf, cal, dat, bch, ief and itf. Perkinelmer launches labchip gx touch and gxii touchtm. Caliper gx ii system application evaluation perkinelmer yumpu. The high resolution labchip is designed to be compatible with the glycan screening assay and low molecular weight protein assay on the labchip gxii microfluidic capillary electrophoresis cesds platform. Right click on the link to the file and choose save target as and save the zip file to your desktop. Contact the perkinelmer center for training and development for information. Protein purification automated small scale purification. Perkinelmer analytical solutions for accelerated process development. Labchip gxii touch ht protein characterization system perkinelmer.
The gxii touch system helps to accelerate the development of biotherapeutic drugs by automating the protein characterization process. Lapchip gxii touch protein assay protfolio mediray. Both systems combine calipers assay technology with advanced data analysis and visualization software. Use the links below to quickly find your software solution download. Discover the effortless versatility of an instrument that makes it easy to handle any sample matrix, any interference, and any particle size. Run up to 400 samples with 4 primes for sample batch sizes up to 96 or 8 primes for sample batch sizes of 48 samples or fewer. This flexible instrument supports multiple assays for characterizing both proteins and nucleic acids.
Labchip gx touch nucleic acid analyzer perkinelmer. Pe labchip gx touch ht dnarna characterization systemyear 2016. Product service and customer support plans perkinelmer offers a full range of services to ensure your success. Electrophoresis separation for high sensitivity dnarna analysis. High resolution labchip gxii, touch ht perkinelmer.
Increase efficiency and accelerate protein workflows with. The labchip gxii touch protein characterization system provides the complete. Labchip gxii touch protein characterization system. Protein sizing and quantification on a microchip is achieved by integration of the sample 3,4 automatic sampling directly from a 96 or 384well microtiter plate software 21cfr part 11 determines the size, quantification, and purity. Analysis of each sample is fast, occurring in 40 sec, and the samples are analyzed directly from a 96well plate. Whether it is quantitating monoclonal antibody titers, optimizing protein expression conditions, or rapidly screening igg nglycan profiles, the labchip gxii is the perfect benchtop tool to. The glycan screening reagent kit is designed for the labchip gxii, labchip gxii touch ht and labchip gxii touch 24 microfluidic systems. Perkinelmer has led the way for over 25 years with powerful software and informatics solutions.
In the field of vaccines and biologics, the labchip gxii has been widely adopted across the discovery and development pipeline by a large number of pharmaceutical and vaccine developers to improve. Rapid analysis of nglycans on the labchip gxii microchipce platform abstract a high throughput microchipce method on the labchip gxii has been developed for profiling nglycans from recombinant igg antibodies. It allows the complete assessment of rna quality for better gene expression data. After the labchip instrument optics detect the laserinduced fluorescent signal, easy to use system software automatically analyzes the data and provides the user. The labchip gxii touch protein characterization system offers an automated alternative to traditional methods by streamlining slab gel electrophoresis, while also providing the increased throughput and data quality required by biotherapeutics and genomics workflows. Improving the efficiency of metagenomic analysis of stool samples 2018 automated ngs library preparation with covaris focusedultrasonicator workflow solution 2018. Ongoing analytical measurement of nutritional additives and the total micronutrient content in the cereal is one way in which food producers can quantify the quality and consistency of their cereal products. From our original factory warranty through a comprehensive line of customer support plans, perkinelmer offers you field service engineers and inhouse specialists who are. The labchip gx touch nucleic acid analyzers microfluidic technology generates reproducible, highresolution data and is optimal for.
The labchip gx rna assay analysis determines the quality of the rna sample by measuring the relative amounts of know rna fragments relative to the total rna present in the sample. Labchip gxii touch biotherapeutics how a chip works youtube. Rapid analysis of nglycans on the labchip gxii microchip. Caliper life sciences introduces labchip gx and gxii. Credit card and paypal payments are accepted, but may be. Application note analysis of pb, dc, and as in spice mixtures with an inherent toxicity, a tendency to accumulate in the food chain and a particularly low removal rate through excretion, lead pb, cadmium cd and arsenic as cause harm to humans even at low concentrations. Read perkinelmers applied genomics blog to learn how to improve the efficiency of your work in the applied genomics field. With 96well and 384well plate compatibility and the ability to select single wells at any location in a plate, the labchip gx and gxii systems provide researchers with unmatched throughput, flexibility, and performance. The labchip gx system can enhance genomics research process by precisely quantifying nucleic acids. Blabchip gx touch gxii touch user manual perkinelmer, inc.
Caliper labchi p gx instruments contain class 3b laser diodes. With 96well and 384well plate compatibility and the ability to select single wells at any location in a plate, the labchip gx and gxii systems provide researchers with flexibility and performance. Proteinsimple ice cfr software is used for system control, data acquisition and collection of critical audit information. Caliper gx ii system application evaluation perkinelmer. Labchip gxii separation is based on size, with the resolution ranging from 14 to 300 kda. White paper streamlining materials innovation processes with electronic lab notebook eln and data analytics for optimum efficiency. In this method pngase freleased nglycans in a 96well microtiter plate are fluores. This paper explores the numerous challenges materials scientists and engineers face, from the time it takes to bring new materials to market to the difficulties delivering suitable formulations and testing against specified criteria, and how. The labchip gxgxii electrophoresis systems use a single sipper microfluidic chip to aspirate samples directly from 96 or 384well plates. Our biotherapeutics research products are designed for consistent and reproducible results, and are a component of glpcompliant processes in the worlds leading pharmaceutical, biotechnology and contract research organizations. Labchip gx touch nucleic acid analyzer perkinelmer applied. Pe labchip gx touch ht dnarna characterization system.
This approach can lead to the development of robust. Automated electrophoresis for protein characterization figure 1. It provides a fast, economically efficient means to assess the main glycoforms of igg and related proteins. Leveraging microfluidic electrophoretic separation technology, the labchip gxii touch system enables rapid characterization with minimal sample preparation setup and sample input volume.
The files used by the ice cfr software are created using a file format unique to the software. The labchip gx is the most accurate and advanced nucleic acid separations system available. The instrument optics detect samples by laserinduced fluorescence. Labchip small rna assay perkinelmer applied genomics.
Selexis sa, 14 chemin des aulx, ch1228 plan les ouates. Labchip gx is a program that provides support for the high sensitivity dnarna analysis, dna smear analysis, rna and gdna integrity analysis. The labchip gxii touch protein characterization system provides the complete solution for reproducible quantitation, molecular weight sizing and percent purity analysis of protein samples. Biotherapeutics allow researchers to explore new mechanisms for the treatment of a variety of conditions. A high throughput capillary electrophoresis method to. Microfludic on a chip offers new areas of development and bioterapeutic studies. The software contains an application security module for user account management and for access of controls to. Labchip gx touch nucleic acid analyzer dna and rna quantitation and sizing can be done in seconds using automated capillary electrophoresis separation.
Increase efficiency and accelerate protein workflows with the labchip gxii. The labchip gx touch gxii touch are classified as a class 1 device because the lasers are appropriately enclosed embedded and indicated with warning labels. Both systems combine calipers highly reproducible assay technology with advanced data analysis and visualization software. Labchip gxii for high throughput characterization of. After connecting a pc and opening the labchip software the status indicator. Labchip gx gxii touch instruments contain class 3b laser diodes. The labchip gx is classified as a class 1 device because the lasers are appropriately enclosed embedded and indicated with warning labels. Purification process development labchip gxii protein chip labchip gxii system workflow. The leader in this field is caliper lifescience, recently acquired by perkinelmer. Improving characterization of monoclonal antibodies. The computer supplied with the labchip gx instrument has internal. Like its predecessor the labchip90, the gx suite of instruments utilizes perkinelmers innovative microfluidics technology to perform reproducible, highresolution, eletrophoretic separations. With our preverified assays, there is no or little method development needed. The labchip gx touch nucleic acid analyzers microfluidic technology generates reproducible.
The caliper life sciences labchip gxii system delivers quantitative, highthroughput protein analysis necessary to truly accelerate these development work flows. The labchip gxii touch protein characterization system offers an automated alternative to traditional methods by streamlining slab gel electrophoresis, while also providing the increased throughput and data quality required by biotherapeutics and genomics. The most popular device using microfluidic chip chemistry and technology is labchip gxii, which is a standard in most biomedical labs nowadays. Perkinelmer solutions for accelerated biotherapeutic process development automation automated small scale purification of biotherapeutic proteins labchip gxii touch automated electrophoretic separations of rna, dna, proteins and glycans labchip ds high throughput microfluidic uvvis for research use only. Labchip gxii touch protein characterization system perkinelmer. Automated electrophoresis for protein characterization. There was a 4 log linear range of detection lower limit of detection was about 10 pg. The information in this section is from caliper labchip gxgx ii user manual how the caliper software analyzes rna data. Our protein detection assays allow you to optimize performance, simplify workflows, and increase throughput. Labchip gxii touch ht protein characterization system. The efficient production of these nutritionally fortified breakfast cereals requires careful formulation and uniformity batch to batch. The labchip gxgxii systems offer researchers an automated alternative by streamlining the multiple, manual steps of slab gel electrophoresis, while also providing the throughput and data quality. The system can be located in a designated laboratory room to limit system access to authorized individuals 21 cfr 11.
Touch protein characterization system and assays for doe development to. The labchip gxii is a complete solution for consistent and precise analysis of protein samples, and is an ideal instrument for protein research users. Protein detection and quantification is required for the development of proteinbased therapeutics, as well as research into cell signaling, growth factors, and a variety of disease states. The labchip gxp security software provides users with with electronic signature, electronic record retention, and access management to streamline meeting requirements for compliance. Import labchip gx or labchip 90 data files with ease. When powered on, the chip, eject, and status indicators labchip gxii light up. For example, automating the characterization process allows multiple, critical quality attributes to be obtained significantly faster.
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